{"id":1223373397687767000,"conversation_id":"1223373234424483842","created_at":1580509921000,"date":"2020-01-31","time":"22:32:01","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Based in Cambridge, MA","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1223373397687767040","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775881422266400,"conversation_id":"1222775854452875266","created_at":1580367462000,"date":"2020-01-30","time":"06:57:42","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...in healthcare goes generic. All the drugs we haven’t yet invented that will eventually go generic are our best hope & value when we consider the diseases that will otherwise keep us worried, pained, and spending a fortune on doctors & hospitals, which never go generic.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775881422266368","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775880352780300,"conversation_id":"1222775854452875266","created_at":1580367462000,"date":"2020-01-30","time":"06:57:42","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And lastly, this is not a rationale for unlimited drug prices. For all the rhetoric & even with clear examples of abuses, moderate profit margins show industry doesn’t systematically price gouge. Competition (lots of it) & drugs going generics keep costs in check. Nothing else...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775880352780289","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775879279042600,"conversation_id":"1222775854452875266","created_at":1580367462000,"date":"2020-01-30","time":"06:57:42","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"So, Congress, I urge you to beware of those promising their formulas will define the “right and fair prices”. They will likely grossly undervalue what you know to be valuable. And when innovation is undervalued, it doesn’t get done. You know that.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775879279042560","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775878209417200,"conversation_id":"1222775854452875266","created_at":1580367462000,"date":"2020-01-30","time":"06:57:42","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"... and to do it with treatments that will be inexpensive generics for the long run. So what’s that peace of mind worth? A lot. I won’t say priceless. But you will never find a formula that captures its value.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775878209417216","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775876963704800,"conversation_id":"1222775854452875266","created_at":1580367461000,"date":"2020-01-30","time":"06:57:41","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...allow us to say that we’ve collectively “vaccinated” ourselves of worrying that our child might suffer from them. It’s within our reach to say my child won’t die of breast cancer, lupus, heart disease, at least not before a ripe old age...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775876963704832","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775875931951000,"conversation_id":"1222775854452875266","created_at":1580367461000,"date":"2020-01-30","time":"06:57:41","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And one more thing... if it seems that I’m making a narrow case for the value of vaccines against pandemics, I’m not. I’m hoping to inspire you with a bigger, beautiful idea that all the drugs and other technologies we are developing for many diseases might...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775875931951104","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775874887483400,"conversation_id":"1222775854452875266","created_at":1580367461000,"date":"2020-01-30","time":"06:57:41","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And making sure that all of those products go generic and remain expensive after they have gone generic (with new regulations in some cases, as I’ve proposed) is how we guarantee that America gets great value from its investment, like paying off a mortgage.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775874887483392","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775873839030300,"conversation_id":"1222775854452875266","created_at":1580367461000,"date":"2020-01-30","time":"06:57:41","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"It would be like making the family whose house is burning pay out of pocket to fund the fire department that helps all of us sleep better. Insurance premiums and taxes spread across a mostly healthy, working population is how we can afford the fruits of biotechnology.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775873839030272","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775872744280000,"conversation_id":"1222775854452875266","created_at":1580367460000,"date":"2020-01-30","time":"06:57:40","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"It’s wrong to ask the few vulnerable among us to pay, as insurance plans do when they impose high out of pocket costs, for the biotechnology vaccine infrastructure that brings peace of mind to all of us.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775872744280064","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775871716626400,"conversation_id":"1222775854452875266","created_at":1580367460000,"date":"2020-01-30","time":"06:57:40","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Yet we mustn’t ask vulnerable, sick, and poor patients to pay out of pocket what they can’t afford, as our broken insurance system increasingly has (a practice Congress can outlaw just as it eliminated denials based on pre-existing conditions).","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775871716626435","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775870676504600,"conversation_id":"1222775854452875266","created_at":1580367460000,"date":"2020-01-30","time":"06:57:40","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"As a society, it’s all our money... we can collectively afford to fund a vibrant biotechnology sector to develop new medicines that patients currently need as well as vaccines that we hope we’ll never use. Health economists don’t value our peace of mind, but YOU know it’s value.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775870676504578","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775869623734300,"conversation_id":"1222775854452875266","created_at":1580367460000,"date":"2020-01-30","time":"06:57:40","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Just as spending on iPhones supports the development of technologies that make their way into national defense, healthcare, and education, similarly spending on national defense makes its way into iPhones, medicine, and kitchen appliances. (Eg NASA/Apollo tech helps burn victims)","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775869623734273","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775868612915200,"conversation_id":"1222775854452875266","created_at":1580367459000,"date":"2020-01-30","time":"06:57:39","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"3) and that same insurance premiums, out of pocket spending, and healthcare taxes are spent on many other, seemingly unrelated, medicines, such as for rare genetic disorders and cancer, but which are based on technologies that can be applied to combat emergent viruses.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775868612915201","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775867572617200,"conversation_id":"1222775854452875266","created_at":1580367459000,"date":"2020-01-30","time":"06:57:39","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"2) insurance premiums and out of pocket spending and healthcare related taxes (Medicare/caid) go to pay for commercially sold vaccines (eg flu), keeping the giant companies with massive vaccine production facilities in business and well practiced in making vaccines...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775867572617218","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775866566025200,"conversation_id":"1222775854452875266","created_at":1580367459000,"date":"2020-01-30","time":"06:57:39","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"We pay for the security of having vaccine and antiviral infrastructure in three ways: 1) the US Government broadly taxes Americans and provides research grants for certain programs to biotech companies...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775866566025216","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775865513324500,"conversation_id":"1222775854452875266","created_at":1580367459000,"date":"2020-01-30","time":"06:57:39","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...or do we recognize that ideally the cost per patient would be infinite because we would spend hundreds of millions to develop the vaccine, maybe more, but prefer to never have to use it?","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775865513324545","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775864439517200,"conversation_id":"1222775854452875266","created_at":1580367458000,"date":"2020-01-30","time":"06:57:38","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...in most cases we end up not needing the product (and the company sells nothing)? If such vaccines end up being deployed narrowly, just to ring-fence a few early patients, do we look at the high cost per patient and say “that’s outrageous! Its not cost-effective!”...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775864439517187","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775855384014800,"conversation_id":"1222775854452875266","created_at":1580367456000,"date":"2020-01-30","time":"06:57:36","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Consider the hit to the economy of just the possibility of a pandemic. What’s it worth to the world to have a vibrant vaccine industry that can quickly respond to a threat like SARS, MERS, and this new coronavirus quickly even if...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775855384014849","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222775854452875300,"conversation_id":"1222775854452875266","created_at":1580367456000,"date":"2020-01-30","time":"06:57:36","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"What’s a vaccine worth? Congress- please consider this. If you believe in controlling drug pricing with a formula that calculates value using typical ICER/QALY-based math, consider that such tools don’t capture the general anxiety whenever a pandemic looms.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":4,"likes_count":10,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222775854452875266","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222523264922275800,"conversation_id":"1222523261449318400","created_at":1580307234000,"date":"2020-01-29","time":"14:13:54","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Now it’s critical that payers, including employers, actually adopt this proposed plan. So many even better diabetes drugs are in the pipeline and seeing all patients being able to get available treatments would be an inspiration for innovators.","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222523264922275840","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222349745026424800,"conversation_id":"1222349739603132418","created_at":1580265864000,"date":"2020-01-29","time":"02:44:24","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And if you’ve bought a copy and are finished with it, consider leaving it behind in your doctor’s waiting room. Odds are, someone will come along who could use some help figuring out who exactly to be angry at and how to fix our broken system.","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222349745026424834","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222349743420006400,"conversation_id":"1222349739603132418","created_at":1580265863000,"date":"2020-01-29","time":"02:44:23","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Republican friend? Definitely. Democrat? Might want to double the dose. Socialist? Yes, and then pour yourself a drink. Someone who loves game theory, this book is filled with it. A firefighter cousin? I use a fire dept analogy.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222349743420006400","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222349742732193800,"conversation_id":"1222349739603132418","created_at":1580265863000,"date":"2020-01-29","time":"02:44:23","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...the uncle who works at an insurance company and laments all the patients whose treatments he’s forced to turn down... the book is for him. A friend who’s always talking about the debates... the book will really open her eyes to what’s not being said on that stage.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222349742732193793","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1222349742002331600,"conversation_id":"1222349739603132418","created_at":1580265863000,"date":"2020-01-29","time":"02:44:23","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Grandma is outraged about high insulin prices... I wrote it for her. Nephew is thinking about going into biotech... I wrote it for him. Sister is joining a political campaign and is talking about drug price controls... definitely wrote it for her. And then there’s...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1222349742002331648","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606629600366600,"conversation_id":"1221606574231302145","created_at":1580088691000,"date":"2020-01-27","time":"01:31:31","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Unlike spending on hospital, which is an eternal rent, branded drugs will go generic (and I propose regulations for the few that don’t yet), and remain useful forever, offering us a bargain. Our parents paid off the drugs that are our generics today. Shall we invest for our kids?","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":2,"likes_count":6,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606629600366592","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606627943551000,"conversation_id":"1221606574231302145","created_at":1580088691000,"date":"2020-01-27","time":"01:31:31","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Back to question 2. Though America can afford and should afford (to signal their importance to drug developers) to spend $271B on branded drugs, using proper insurance to shield patients from that cost, can’t we spend less? We overlook that we soon will.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606627943550976","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606626295238700,"conversation_id":"1221606574231302145","created_at":1580088690000,"date":"2020-01-27","time":"01:31:30","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And only a fraction of OOP costs are unaffordable; many people are reasonably healthy, have jobs, and can cover their OOP costs. If we shifted even $20B of OOP costs to premiums or taxes to ease the burden on the hardest hit patients, we would solve affordability. Tiny shift.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606626295238656","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606624642637800,"conversation_id":"1221606574231302145","created_at":1580088690000,"date":"2020-01-27","time":"01:31:30","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"It would take ~2% increase in premiums to make branded drugs affordable to patients. Considering our nation’s $17.6B in personal income, it would take a 0.3% rise in taxes to pay for all OOP costs. Not impossible - just a choice.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606624642637825","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606623094898700,"conversation_id":"1221606574231302145","created_at":1580088689000,"date":"2020-01-27","time":"01:31:29","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"In the context of nearly $3T collected in total in taxes and insurance premiums for healthcare (the vast majority going to doctors and hospitals), leaving out the $61B (2%) that makes drugs unaffordable to some seems a bit arbitrary. You can’t say that 2% is unaffordable.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":2,"likes_count":7,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606623094898688","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606621568290800,"conversation_id":"1221606574231302145","created_at":1580088689000,"date":"2020-01-27","time":"01:31:29","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"The point is that $271B is affordable for America and can be affordable for patients but only if patients have proper insurance. The trouble is that right now only about $210B is sourced from taxes and premiums and $61B is charged to patients as OOP costs. (Source: IQVIA)","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":4,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606621568290818","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606619798220800,"conversation_id":"1221606574231302145","created_at":1580088689000,"date":"2020-01-27","time":"01:31:29","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Let’s say you need insulin. Your plan has negotiated a big rebate from the drug company for that insulin. You have to pay full price out of your deductible but your insurance keeps the rebate. Congress knows about this tactic and is working to close it.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606619798220800","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606618133037000,"conversation_id":"1221606574231302145","created_at":1580088688000,"date":"2020-01-27","time":"01:31:28","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Congress outlawed that practice. So plans switched to increasing deductibles and copays, more broadly discriminating against the sick when that’s who it’s for. There are even loopholes so clever that an insurance company can make more off of you when you get sick. Here’s how:","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606618133037062","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606615146737700,"conversation_id":"1221606574231302145","created_at":1580088688000,"date":"2020-01-27","time":"01:31:28","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"They used to discriminate on the basis of pre-existing conditions (remember?), refusing to pay for a woman’s treatment for recurrent breast cancer because she had beaten it once before when she was on a different plan. That kept premiums down but left patients hanging.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606615146737667","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606613536116700,"conversation_id":"1221606574231302145","created_at":1580088687000,"date":"2020-01-27","time":"01:31:27","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"But instead of competing to charge the lowest premiums by trying to figure out how to deliver proper insurance (ie. pay for treatments you need when you fall ill) more efficiently, insurers keep costs down by jamming plans full of loopholes. Like less honest Swiss cheese.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606613536116736","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606612084953000,"conversation_id":"1221606574231302145","created_at":1580088687000,"date":"2020-01-27","time":"01:31:27","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And of course all patients need to have insurance with low OOP costs. That can be called universal insurance, but that doesn’t mean that it must be a single government plan (ie single payer, Medicare for All). Insurance plans can, should, and do compete on quality.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606612084953088","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606610470084600,"conversation_id":"1221606574231302145","created_at":1580088686000,"date":"2020-01-27","time":"01:31:26","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"So the answer to the 3rd question is “insurance”.  And when a patient can’t afford their treatments, it’s because their insurance has failed to make it affordable. Current proposals in Congress to lower out of pocket costs are right on the money. That will solve affordability.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":7,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606610470084608","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606608284921900,"conversation_id":"1221606574231302145","created_at":1580088686000,"date":"2020-01-27","time":"01:31:26","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"You could cut all drug prices by 90% and you would still have Americans struggling to afford their cancer treatments, going without. It should be clear that neither drugs nor any healthcare really is affordable to patients without some kind of insurance to spread the risk/cost.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":4,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606608284921857","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606606695288800,"conversation_id":"1221606574231302145","created_at":1580088686000,"date":"2020-01-27","time":"01:31:26","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Most of us spend most of our lives healthy. We earn most of our lifetime income while we are healthy, but we tend to fall ill later, disproportionately in our retirement. Some get sicker than others. Some get sick earlier than others. No one can plan for that risk alone.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606606695288838","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606605109833700,"conversation_id":"1221606574231302145","created_at":1580088685000,"date":"2020-01-27","time":"01:31:25","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"How can we spread $271B (or even $200B) across America so that patients can afford drugs. If only patients (those now sick) were made to pay out of pocket (OOP) for medicine (let alone the rest of healthcare), they couldn’t afford it. Healthcare is unaffordable out of pocket.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606605109833733","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606600831590400,"conversation_id":"1221606574231302145","created_at":1580088684000,"date":"2020-01-27","time":"01:31:24","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Whether we need to spend $271B is another question. Maybe we don’t need to spend so much if the same drugs can be had for less. It’s not the most important question (but we’ll get back to it) because even if the right number is $200B, what matters is the next question.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606600831590400","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606599468441600,"conversation_id":"1221606574231302145","created_at":1580088684000,"date":"2020-01-27","time":"01:31:24","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"So whether we want America to afford $271B on drugs is a question of whether we want to incentivize and fuel the discovery and development of new drugs for unmet needs. I look at what science can do and how much suffering there is that science can solve and I vote yes.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":6,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606599468441600","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606598071799800,"conversation_id":"1221606574231302145","created_at":1580088683000,"date":"2020-01-27","time":"01:31:23","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"So the drug industry doesn’t invest very much in antibiotics. When America reassures scientists and investors that it needs new antibiotics badly enough to pay for them, it will see results. Until then, mere altruism isn’t proving to be as productive.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":1,"likes_count":4,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606598071799809","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606595232174000,"conversation_id":"1221606574231302145","created_at":1580088683000,"date":"2020-01-27","time":"01:31:23","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"The industry however won’t make just any medicine. American hospitals don’t pay much for new antibiotics. They try to make do mostly with older, generic antibiotics and avoid using a better newer medicine, treating it as a last resort. So antibiotics don’t sell well.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606595232174081","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606593667719200,"conversation_id":"1221606574231302145","created_at":1580088682000,"date":"2020-01-27","time":"01:31:22","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"If America didn’t value new medicines, it wouldn’t pay for them. America does pay. So there’s a vibrant drug development industry that serves American patients. The drug industry still sells those same drugs to other countries for less, but only for marginal profit.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":5,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606593667719169","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606592191385600,"conversation_id":"1221606574231302145","created_at":1580088682000,"date":"2020-01-27","time":"01:31:22","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"It’s a basic truth of markets that what we spend money on as a society is a reflection of what we value and want. If we like movies, we pay for them, and Hollywood gives us more of what we want. When we stopped buying vinyl records, fewer got made.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606592191385600","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606585333702700,"conversation_id":"1221606574231302145","created_at":1580088680000,"date":"2020-01-27","time":"01:31:20","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Given that $271B is affordable to America, we can discuss three things... 1) whether we want to spend that on branded medicines, 2) whether we have to spend that much, and if yes to both, 3) how to spread those costs so that they don’t fall too much on patients.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":5,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606585333702656","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606583945265200,"conversation_id":"1221606574231302145","created_at":1580088680000,"date":"2020-01-27","time":"01:31:20","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Therefore, anyone who says that America, given the size of its economy, can’t afford the 1.3% of GDP or 1.5% of personal income on new (branded) drugs is presenting as fact what is merely their judgment as a fact. We are all free to judge for ourselves.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":2,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606583945265152","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606582586421200,"conversation_id":"1221606574231302145","created_at":1580088680000,"date":"2020-01-27","time":"01:31:20","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Two products of equal price are equally affordable to someone with a given amount of money in their pocket. $271B spent on drugs is no more or less affordable that $271B spent on the military, hospitals, schools, roads, entertainment, food, housing, or just bureaucracy.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":4,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606582586421248","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221606574231302100,"conversation_id":"1221606574231302145","created_at":1580088678000,"date":"2020-01-27","time":"01:31:18","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"First thread of two on drug pricing... (second will be more of an FAQ). I invite pressure testing of each point. Branded drugs cost America $271B in 2018, 1.3% of America’s $20.5 trillion GDP or 1.5% of American’s $17.6T total personal income $17.6 trillion.","mentions":[],"urls":[],"photos":[],"replies_count":3,"retweets_count":28,"likes_count":71,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221606574231302145","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010613456994300,"conversation_id":"1221010572579352577","created_at":1579946590000,"date":"2020-01-25","time":"10:03:10","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"And when those drugs go generic, they bring value to America and the world unlike anything else in healthcare. Drugs going generic is the price control we’ve long had and what we should continue to rely on. That’s #thebiotechsocialcontract","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":0,"likes_count":3,"hashtags":["#thebiotechsocialcontract"],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010613456994304","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010611326406700,"conversation_id":"1221010572579352577","created_at":1579946589000,"date":"2020-01-25","time":"10:03:09","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"We need to reform our broken insurance system so that all patients can afford what their doctors prescribe. That means everyone is covered with plan that have low out of pocket costs. Then all of America can support innovation without so burdening patients as we do now.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010611326406656","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010609229176800,"conversation_id":"1221010572579352577","created_at":1579946589000,"date":"2020-01-25","time":"10:03:09","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"So when it comes to biomedical progress, America First still yields gifts for all humanity. That doesn’t happen with any other part of healthcare. A hospital in America can’t help all the kids with SCD in Africa. We need to see how different drugs are from the rest of healthcare.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010609229176833","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010607417254000,"conversation_id":"1221010572579352577","created_at":1579946588000,"date":"2020-01-25","time":"10:03:08","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"But once these drugs go generic, they are inexpensive to the whole world. They belong to the whole world like books and music whose copyright has expired belong to the world. There is a lot of sickle cell disease in the world (#africa) and those patients will now get help too.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":["#africa"],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010607417253888","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010605676597200,"conversation_id":"1221010572579352577","created_at":1579946588000,"date":"2020-01-25","time":"10:03:08","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"One more thing... while it feels unfair that other countries don’t pay a fair share for new drugs to incentivize further drug discovery, what little they do pay helps offset America’s cost for getting the drugs that Americans need. W/o America’s willingness to pay, no new drugs.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010605676597254","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010602358923300,"conversation_id":"1221010572579352577","created_at":1579946587000,"date":"2020-01-25","time":"10:03:07","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"But ICER, indeed some drugs don’t go generic, making your math less wrong (though how precisely can one turn kids into a formula?). The solution there is contractual genericization (see the book) instead of discouraging research by declaring such drugs cost-ineffective.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010602358923265","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010599829811200,"conversation_id":"1221010572579352577","created_at":1579946586000,"date":"2020-01-25","time":"10:03:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"As for the discount rate, 3% means our grandchildren count. 2% makes them count more and even acknowledges our great-grandkids. There isn’t a “right” number as much as one that reflects how much we care about future generations. Our parents left us with great generics. Thank you.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010599829811200","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010596361011200,"conversation_id":"1221010572579352577","created_at":1579946586000,"date":"2020-01-25","time":"10:03:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Paying for drugs that eventually go generic is like paying off a higher mortgage on a house so that you can stop paying rent forever. If you didn’t factor in living inexpensively in the house after the mortgage is paid off, you would just keep renting.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010596361011200","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010595127988200,"conversation_id":"1221010572579352577","created_at":1579946585000,"date":"2020-01-25","time":"10:03:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Never once in all the caveats and factors ICER discussed in 194 pages did they mention that these drugs will someday go generic (unlike all the surgeries these kids need). Yet they mention that current standard of care (hydroxyurea) is generic and cheap, so they get the concept.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010595127988224","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010593836081200,"conversation_id":"1221010572579352577","created_at":1579946585000,"date":"2020-01-25","time":"10:03:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Where they to model in genericization and a steep price drop after 10-15 years, ICER’s estimate would fall by 50-65%, before considering savings on hospital care. And when you factor in those savings, then you can even get net savings for society. That’s value!","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010593836081152","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010592548429800,"conversation_id":"1221010572579352577","created_at":1579946585000,"date":"2020-01-25","time":"10:03:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Drugs permanently upgrade human health, but their high cost are temporary. They are made affordable to all patients with proper insurance (sadly, America’s system can be heartless to some by charging high out of pocket costs, which Congress must lower with insurance reform).","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010592548429824","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010591281819600,"conversation_id":"1221010572579352577","created_at":1579946584000,"date":"2020-01-25","time":"10:03:04","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Yet they don’t consider that drugs go generic, becoming inexpensive & continuing to extend and improve lives (as ICER acknowledges these drug do). They assume drugs stay expensive forever. That error adds up to make the drugs seem more costly than they are in the long run.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010591281819648","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010589973172200,"conversation_id":"1221010572579352577","created_at":1579946584000,"date":"2020-01-25","time":"10:03:04","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"At 3%, the future matters. Our grandchildren matter. (At 10%, which is more what financial markets might use, only the next 20 years count and mostly the next 10). 2% is better (I explain below), but still, mathematically, ICER shows some heart.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010589973172224","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010588597473300,"conversation_id":"1221010572579352577","created_at":1579946584000,"date":"2020-01-25","time":"10:03:04","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"In its report, ICER uses a societal 3% discount rate to look at the cost and benefits of three new drugs on the lives of patients with sickle cell. That means that a dollar and a saved life 20 years from now counts for something today. True. They do.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010588597473280","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1221010587217551400,"conversation_id":"1221010572579352577","created_at":1579946583000,"date":"2020-01-25","time":"10:03:03","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"This is objectively #badmath with consequences. Undervaluing an approved drug signals you will undervalue further research. An academic makes a mistake, people suffer. ICER says that SCD community has historically been “neglected”, “betrayed”. And ICER did just that. Here’s how:","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":0,"likes_count":6,"hashtags":["#badmath"],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1221010587217551360","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1220349998434521000,"conversation_id":"1220349993824989185","created_at":1579789087000,"date":"2020-01-23","time":"14:18:07","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"I’m not saying there are no good uses of copays... just want to beat up ideas with y’all. If you know some academics and game theorist, pull them in. They love this stuff.","mentions":[],"urls":[],"photos":[],"replies_count":3,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1220349998434521088","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1220349995871764500,"conversation_id":"1220349993824989185","created_at":1579789086000,"date":"2020-01-23","time":"14:18:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Eg, when a drug goes generic, using a high copay for the brand will encourage patients to opt for the generic. But, how about all payers just drop the brand, basically consider it one of many generics, and fill script with cheapest generic? No nudge needed.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1220349995871764480","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1220349993824989200,"conversation_id":"1220349993824989185","created_at":1579789086000,"date":"2020-01-23","time":"14:18:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Let’s brainstorm: can you think of cases when healthcare deductibles and copays serve a useful propose that can’t be achieved in other ways?","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":1,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1220349993824989185","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425906416083000,"conversation_id":"1219425895909404672","created_at":1579568766000,"date":"2020-01-21","time":"01:06:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Having drugs go generic is in society’s best interests, he says. “If we don’t ensure that high drug costs are a finite mortgage instead of an infinite rent, then Congress will be right to regulate those rents down,” he says.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425906416082945","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425904276930600,"conversation_id":"1219425895909404672","created_at":1579568766000,"date":"2020-01-21","time":"01:06:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"“When I’m funding the development of a new drug, I don’t count on revenues 20 years after approval. I have to discount anything that far away &, because my discount rate is high (ie, 8–12%), factors that are more than 10-15 years away are essentially irrelevant to my decision...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":3,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425904276930560","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425903559790600,"conversation_id":"1219425895909404672","created_at":1579568765000,"date":"2020-01-21","time":"01:06:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"“If we don’t sacrifice the excessively long revenue tails some companies have figured out how to append to old drugs, society will simply squash all revenues down with indiscriminate price controls,” he says.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425903559790598","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425902725083100,"conversation_id":"1219425895909404672","created_at":1579568765000,"date":"2020-01-21","time":"01:06:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"“If companies exploit the patent system to achieve infinite monopolies, it might be legal, but it’s at odds with the spirit of competitive, free-market economics (i.e., capitalism) and laws can be changed to block such exploitation of the patent system,” he says.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425902725083137","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425901928206300,"conversation_id":"1219425895909404672","created_at":1579568765000,"date":"2020-01-21","time":"01:06:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"“If we don’t sacrifice the excessively long revenue tails some companies have figured out how to append to old drugs, society will simply squash all revenues down with indiscriminate price controls,” he says.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425901928206337","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425900581703700,"conversation_id":"1219425895909404672","created_at":1579568765000,"date":"2020-01-21","time":"01:06:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"\"Whether they are called equivilars, me-too drugs, or fast-followers, having similar drugs compete on price is a proven model that saves society money, although, in the end, nothing will beat the value of all those drugs just going generic,\" he says.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425900581703680","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425899864645600,"conversation_id":"1219425895909404672","created_at":1579568765000,"date":"2020-01-21","time":"01:06:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Here are some excerpts at random... I just cut and paste with my eyes closed... which everyone knows gets around copyright. :)","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425899864645633","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425899059261400,"conversation_id":"1219425895909404672","created_at":1579568764000,"date":"2020-01-21","time":"01:06:04","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"We def need to make a better case to Congress that it can and should help patients afford drugs by reducing out of pocket costs, not using blunt price controls, & to reform what’s wrong with our industry in better ways. Thank you, Agnes, for providing a forum in which to do so.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425899059261446","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1219425897419300900,"conversation_id":"1219425895909404672","created_at":1579568764000,"date":"2020-01-21","time":"01:06:04","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Agnes frames the problem before us perfectly: “People are demanding that the industry define its mission. Is it helping patients or generating profits?  CEOs might argue that they are doing both, but the public and legislators aren’t buying it.”","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1219425897419300864","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1218741152716935200,"conversation_id":"1218741122970853376","created_at":1579405508000,"date":"2020-01-19","time":"03:45:08","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"Anyone can pitch in by researching the origins of one of the drugs listed in the article and tweeting a shoutout to the inventors for permanently upgrading our generic drug mountain. And just maybe that will make companies proud to let their drugs go generic without undue delay.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1218741152716935176","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1218741145909506000,"conversation_id":"1218741122970853376","created_at":1579405506000,"date":"2020-01-19","time":"03:45:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"...just as many Americans think their lisinopril comes from Lupin or Sandoz and have never heard of the chemist Arthur Patchett and the team he led at Merck that developed that life saving drug, the most commonly prescribed generic (lowers blood pressure).","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":1,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1218741145909506049","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1218741144382820400,"conversation_id":"1218741122970853376","created_at":1579405506000,"date":"2020-01-19","time":"03:45:06","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"If we took authorship for granted the way we do inventorship, then students would think Pride and Prejudice were written by Penguin Classics...","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":2,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1218741144382820353","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1218696297148047400,"conversation_id":"1218691208316440577","created_at":1579394814000,"date":"2020-01-19","time":"00:46:54","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"If you run a company (in the Boston area) and have colleagues starting their careers, let them know about the course. They will come back to you better equipped. We want the next generation to benefit from all our lessons learned if they are to build on today’s foundation.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":1,"likes_count":7,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1218696297148047360","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1218615814473113600,"conversation_id":"1218615814473113600","created_at":1579375625000,"date":"2020-01-18","time":"19:27:05","timezone":"UTC","user_id":1130959251671834600,"username":"peterkolchinsky","name":"Peter Kolchinsky","place":"","tweet":"A fire department, blaming the cost of the fire truck and water, let a house burn when the family couldn’t pay the copayment! Absurd, is it? Oh wait... I’m thinking about America’s health insurance system. Congress must lower out of pocket costs so insurance becomes... insurance.","mentions":[],"urls":[],"photos":[],"replies_count":7,"retweets_count":18,"likes_count":64,"hashtags":[],"cashtags":[],"link":"https://twitter.com/PeterKolchinsky/status/1218615814473113600","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"1130959251671834624","username":"PeterKolchinsky"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1274892974380499000,"conversation_id":"1274892974380498944","created_at":1592793146000,"date":"2020-06-22","time":"02:32:26","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"I am all for prioritizing senior political leaders for testing as continuity of leadership is a legitimate policy goal. \n\nBut it's reasonable to expect that they won't abuse this privilege by avoiding other precautions and by setting a bad example for the public.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":2,"likes_count":9,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1274892974380498944","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1268397350378254300,"conversation_id":"1268397350378254336","created_at":1591244468000,"date":"2020-06-04","time":"04:21:08","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"The U.S. has never vaccinated its adult population in the numbers needed for COVID-19 herd immunity. Therefore, there's a need for a national COVID-19 vaccine plan -Now.","mentions":[],"urls":[],"photos":[],"replies_count":79,"retweets_count":286,"likes_count":1032,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1268397350378254336","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1262560548484456400,"conversation_id":"1262560548484456451","created_at":1589852866000,"date":"2020-05-19","time":"01:47:46","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"One silver lining of most people working from home is  normalization of kids and pets barging in on Zoom calls. That's a good thing. \n\nHopefully, this will translate to people not freaking out about babies at conferences.","mentions":[],"urls":[],"photos":[],"replies_count":4,"retweets_count":11,"likes_count":129,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1262560548484456451","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1260940809865588700,"conversation_id":"1260940809865588741","created_at":1589466690000,"date":"2020-05-14","time":"14:31:30","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Trying to hire a postdoc for #COVID19 work. A well-meaning administrator involved in the process asked what will the postdoc do after #COVID19; as it may be over soon. \n\nHow endearingly naive 🙂","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":3,"likes_count":57,"hashtags":["#covid19","#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1260940809865588741","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1257143865267630000,"conversation_id":"1257120452058714112","created_at":1588561428000,"date":"2020-05-04","time":"03:03:48","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"*excess not access","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":0,"likes_count":0,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1257143865267630080","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1257125648683995100,"conversation_id":"1257120452058714112","created_at":1588557085000,"date":"2020-05-04","time":"01:51:25","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"*even then it's not a perfect🍎to🍎comparison.\n\nMoreover, the current #COVID19 mortality is in the presence of substantial social distancing measures.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":0,"likes_count":5,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1257125648683995139","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1256804986274676700,"conversation_id":"1256804985012174848","created_at":1588480633000,"date":"2020-05-03","time":"04:37:13","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"(obviously growing involvement of vaccine skeptics in #COVID19 protests is not the only factor that will determine eventual vaccine acceptance)","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":1,"likes_count":5,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1256804986274676736","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1256604190668963800,"conversation_id":"1256584452530110465","created_at":1588432760000,"date":"2020-05-02","time":"15:19:20","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Hep C is another exception, but the pipeline is indeed pretty lousy for most viruses -particularly respiratory viruses.","mentions":[],"urls":[],"photos":[],"replies_count":4,"retweets_count":2,"likes_count":24,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1256604190668963840","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1256584452530110500,"conversation_id":"1256584452530110465","created_at":1588428054000,"date":"2020-05-02","time":"14:00:54","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"With all the discussion of \"modest\" efficacy of Remdesivir and how it reminds of modest effectiveness of Tamiflu, here's the underlying fact: with the exception of HIV, we have a lousy pipeline of antivirals.\n\nWe must do better in terms of discovery and clinical evaluation.","mentions":[],"urls":[],"photos":[],"replies_count":24,"retweets_count":83,"likes_count":350,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1256584452530110465","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1251691404457369600,"conversation_id":"1251691404457369605","created_at":1587261460000,"date":"2020-04-19","time":"01:57:40","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"There's a lot of discussion of America's lost month. The sad fact is that we still don't have sufficient testing. This is more like a lost spring.","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":7,"likes_count":35,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1251691404457369605","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1250823953800671200,"conversation_id":"1250823953800671233","created_at":1587054644000,"date":"2020-04-16","time":"16:30:44","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Have been making media appearances in South Asia as well. Today went back-to-back on Indian and Pakistani channels. A brief moment of trans-border harmony🙂","mentions":[],"urls":[],"photos":[],"replies_count":3,"retweets_count":1,"likes_count":37,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1250823953800671233","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1250792327305666600,"conversation_id":"1250792327305666563","created_at":1587047104000,"date":"2020-04-16","time":"14:25:04","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"One sign that I am on twitter too much: While editing a paper, I typed \"#COVID19\" instead of COVID-19.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":3,"likes_count":80,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1250792327305666563","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1245816628123709400,"conversation_id":"1245816628123709443","created_at":1585860804000,"date":"2020-04-02","time":"20:53:24","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Dear colleagues from adjacent fields. I say this with respect: if you have a brilliant idea on dealing with #COVID19 please reach out to those who do this for a living before writing your think piece; otherwise the rest of us will be cleaning up your mess for years.","mentions":[],"urls":[],"photos":[],"replies_count":14,"retweets_count":87,"likes_count":355,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1245816628123709443","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1245097093053714400,"conversation_id":"1245097093053714433","created_at":1585689254000,"date":"2020-03-31","time":"21:14:14","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"The good news/bad news story of our times: some of the clinical trials are closing because they have quickly met the sample size (due to high burden of #COVID19)","mentions":[],"urls":[],"photos":[],"replies_count":0,"retweets_count":14,"likes_count":23,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1245097093053714433","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1245086182586925000,"conversation_id":"1245086182586925066","created_at":1585686653000,"date":"2020-03-31","time":"20:30:53","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Imagine if we had to go through this pandemic with \nSkype as the only option.","mentions":[],"urls":[],"photos":[],"replies_count":2,"retweets_count":0,"likes_count":17,"hashtags":[],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1245086182586925066","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1244958914015355000,"conversation_id":"1244958914015354880","created_at":1585656309000,"date":"2020-03-31","time":"12:05:09","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Most of what's known about #COVID19 is due to consequential research conducted by Chinese scientists in a raging outbreak. Now that the U.S. has⬆️cases, the baton is with U.S.-based scientists. The quality of our science will influence how the world copes with this pandemic.","mentions":[],"urls":[],"photos":[],"replies_count":1,"retweets_count":12,"likes_count":63,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1244958914015354880","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1244392774251819000,"conversation_id":"1244392774251819010","created_at":1585521331000,"date":"2020-03-29","time":"22:35:31","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"The public health funding gap according to The Trust for America's Health: $4.5 billion. The cost of #COVID19 rescue package $4.2 trillion","mentions":[],"urls":[],"photos":[],"replies_count":5,"retweets_count":38,"likes_count":91,"hashtags":["#covid19"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1244392774251819010","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
{"id":1244338084709351400,"conversation_id":"1244338084709351424","created_at":1585508292000,"date":"2020-03-29","time":"18:58:12","timezone":"UTC","user_id":756713112,"username":"saadomer3","name":"Saad B. Omer","place":"","tweet":"Another benefit of #flatteningthecurve people don't talk about is that it gives us time to evaluate therapies in ongoing trials -which, in turn, could impact survival","mentions":[],"urls":[],"photos":[],"replies_count":5,"retweets_count":72,"likes_count":219,"hashtags":["#flatteningthecurve"],"cashtags":[],"link":"https://twitter.com/SaadOmer3/status/1244338084709351424","retweet":false,"quote_url":"","video":0,"near":"","geo":"","source":"","user_rt_id":"","user_rt":"","retweet_id":"","reply_to":[{"user_id":"756713112","username":"SaadOmer3"}],"retweet_date":"","translate":"","trans_src":"","trans_dest":""}
