# TRIP Database

Mammalian TRansient receptor potential channel-Interacting Protein

TRP channels

- TRPC
  - TRPC1
  - TRPC2
  - TRPC3
  - TRPC4
  - TRPC5
  - TRPC6
  - TRPC7
- TRPV
  - TRPV1
  - TRPV2
  - TRPV3
  - TRPV4
  - TRPV5
  - TRPV6
- TRPM
  - TRPM1
  - TRPM2
  - TRPM3
  - TRPM4
  - TRPM5
  - TRPM6
  - TRPM7
  - TRPM8
- TRPML
  - TRPML1
  - TRPML2
  - TRPML3
- TRPP
  - TRPP1
  - TRPP2
  - TRPP3
- TRPA
  - TRPA1

» Citation

# TRPC1 / interactors

- At a glance
- In detail

- Basic Information
- External Database
- PPI pairs (56)
- Biological Process (5)
- Disease (0)

Name: Short transient receptor potential channel 1 (TRPC1)
Official Symbol: TRPC1 provided by HGNC
Function:
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).

Species | External DB
Name | Description
--- | ---
Entrez Gene | A database that contains genome-centered information
UniprotKB | The central hub for collection of functional information on proteins
DIP | A database that documents experimentally determined PPIs
IntAct | An open source database and software suite for modeling, storing and analyzing molecular interaction data
MINT | A database that collects experimentally verified PPIs in a binary or complex representation
BioGRID | A database of known and predicted PPIs
STRING | An online interaction repository with data
IUPHAR-DB | Integrated pharmacological and pathophysiological information on GPCR and voltage-gated & ligand-gated ion channels
KEGG | A database resource consisting of 16 main databases, categorized into systems information, genomic information, and chemical information
OMIM | A database of human genes and genetic disorders
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM
Human | 7220 | P48995 | DIP-35698N | P48995 |  | 113071 | P48995 | 486 | hsa:7220 | 602343
Mouse | 22063 | Q61056 | DIP-33928N | Q61056 | MINT-4997241 | 204327 | Q61056 |  | mmu:22063 |
Rat | 89821 | Q9QX01 |  |  |  | 250144 | Q9QX01 |  | rno:89821 |

PPI pairs:

BMPR-2 | Bkca | Calcineurin | Calmodulin | Caspase-1 | Caspase-4/Caspase-11 | Cav1.2 | Caveolin-1
Caveolin-3 | Cortactin | D2R | Dystrophin | Enkurin | FGFR-1 | FKBP52/FKBP4 | Gơq/11
Homer | Homer-1 | Homer-2 | Homer-3 | I-MFA | IP3R2 | IP3R3 | MARCKS
MGLUR1 | MxA | NCS-1 | Orai1 | Orai2 | Orai3 | PLCƣ1 | PMCA
Protein 4.1 | RNF24 | RhoA | RyR1 | SERCA2 | SERCA3 | SNAP25 | STIM1
STIM2 | Src | TRPA1 | TRPC3 | TRPC4 | TRPC5 | TRPC6 | TRPC7
TRPP1 | TRPV4 | TRPV6 | VAMP | ơ-actinin | ơ-actinin-1 | ơ1-syntrophin | Ƣ-tubulin-5

Biological Process:

- GO:0007411 : axon guidance
- GO:0051480 : cytosolic calcium ion homeostasis
- GO:0051281 : positive regulation of release of sequestered calcium ion into cytosol
- GO:0051592 : response to calcium ion
- GO:0046541 : saliva secretion

Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
Disease: No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/

Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top

Screening
| Experimental screening | Non-experimental screening | Reference
--- | --- | --- | ---
TRP channel construct | Interactor source
TRP channel |  | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type
TRPC1 |  | BKca | Inference |  |  |  |  |  | Prediction | 19168436
TRPC1 |  | BMPR-2 | Affinity purification-mass spectrometry | Not used as a bait |  | Mouse | Leg muscle | C2C12 lysates |  | 15188402
TRPC1 |  | Calcineurin | Inference |  |  |  |  |  | Prediction | 23228564
TRPC1 |  | Calmodulin | Inference |  |  |  |  |  | Prediction | 11983166
TRPC1 |  | Caspase-1 | Speculation |  |  |  |  |  | Prediction | 24630989
TRPC1 |  | Caspase-4/Caspase-11 | Yeast two-hybrid | Not specified |  | Not specified |  |  |  | 24630989
TRPC1 |  | Cav1.2 | Inference |  |  |  |  |  | Prediction | 21672930
TRPC1 |  | Caveolin-1 | Inference |  |  |  |  |  | Prediction | 10766822
TRPC1 |  | Caveolin-3 | Inference |  |  |  |  |  | Prediction | 18544631
TRPC1 |  | Cortactin | Inference |  |  |  |  |  | Prediction | 19351713
TRPC1 |  | D2R | Yeast two-hybrid | Not used as a bait |  | Human | Fetal brain | cDNA library |  | 18261457
TRPC1 |  | Dystrophin | Inference |  |  |  |  |  | Prediction | 17202249
TRPC1 |  | Enkurin | Inference |  |  |  |  |  | Prediction | 15385169
TRPC1 |  | FGFR-1 | Inference |  |  |  |  |  | Prediction | 15758179
TRPC1 |  | FKBP52/FKBP4 | Inference |  |  |  |  |  | Prediction | 15199065
TRPC1 |  | Gơq/11 | Inference |  |  |  |  |  | Prediction | 10766822
TRPC1 |  | Ƣ-tubulin-5 | Affinity purification-mass spectrometry | Human | Full-length | Bovine | Retinal | Tissue lysates |  | 15935109
TRPC1 |  | Ƣ-tubulin-5 | Yeast two-hybrid | Human | 1-139 | Rat | Brain | cDNA library |  | 15935109
TRPC1 |  | Homer-1 | Inference |  |  |  |  |  | Prediction | 14505576
TRPC1 |  | Homer-2 | Inference |  |  |  |  |  | Prediction | 14505576
TRPC1 |  | Homer-3 | Inference |  |  |  |  |  | Prediction | 14505576
TRPC1 |  | I-MFA | Yeast two-hybrid | Human | 639-750 | Mouse | Embryonic | cDNA library |  | 14530267
TRPC1 |  | I-MFA | Yeast two-hybrid | Human | 639-750 | Human | Fetal kidney | cDNA library |  | 14530267
TRPC1 |  | IP3R2 | Inference |  |  |  |  |  | Prediction | 10970773
TRPC1 |  | IP3R3 | Inference |  |  |  |  |  | Prediction | 10766822
TRPC1 |  | MARCKS | Inference |  |  |  |  |  | Prediction | 24022404
TRPC1 |  | MGLUR1 | Inference |  |  |  |  |  | Prediction | 14614461
TRPC1 |  | MxA | Inference |  |  |  |  |  | Prediction | 15757897
TRPC1 |  | NCS-1 | Inference |  |  |  |  |  | Prediction | 18261457
TRPC1 |  | ơ-actinin | Speculation |  |  |  |  |  | Prediction | 24146259
TRPC1 |  | ơ-actinin-1 | Inference |  |  |  |  |  | Prediction | 17892531
TRPC1 |  | ơ1-syntrophin | Inference |  |  |  |  |  | Prediction | 17202249
TRPC1 |  | Orai1 | Inference |  |  |  |  |  | Prediction | 18326500
TRPC1 |  | Orai2 | Speculation |  |  |  |  |  | Prediction | 22640869
TRPC1 |  | Orai3 | Speculation |  |  |  |  |  | Prediction | 22640869
TRPC1 |  | PLCƣ1 | Inference |  |  |  |  |  | Prediction | 15654973
TRPC1 |  | PMCA | Speculation |  |  |  |  |  | Prediction | 11983166
TRPC1 |  | Protein 4.1 | Inference |  |  |  |  |  | Prediction | 22534489
TRPC1 |  | RhoA | Inference |  |  |  |  |  | Prediction | 12766172
TRPC1 |  | RNF24 | Inference |  |  |  |  |  | Prediction | 17850865
TRPC1 |  | RyR1 | Affinity purification-mass spectrometry | Not used as a bait |  | Rabbit | Fast-twitch muscle | Triad vesicles |  | 18215135
TRPC1 |  | SERCA2 | Inference |  |  |  |  |  | Prediction | 18068335
TRPC1 |  | SERCA3 | Inference |  |  |  |  |  | Prediction | 18068335
TRPC1 |  | SNAP25 | Inference |  |  |  |  |  | Prediction | 15121806
TRPC1 |  | SRC | Inference |  |  |  |  |  | Prediction | 16407161
TRPC1 |  | STIM1 | Inference |  |  |  |  |  | Prediction | 16906149
TRPC1 |  | STIM2 | Speculation |  |  |  |  |  | Prediction | 22640869
TRPC1 |  | TRPA1 | Inference |  |  |  |  |  | Prediction | 23994313
TRPC1 |  | TRPC3 | Inference |  |  |  |  |  | Prediction | 9215637
TRPC1 |  | TRPC4 | Inference |  |  |  |  |  | Prediction | 11301024
TRPC1 |  | TRPC5 | Inference |  |  |  |  |  | Prediction | 11301024
TRPC1 |  | TRPC6 | Inference |  |  |  |  |  | Prediction | 12857742
TRPC1 |  | TRPC7 | Inference |  |  |  |  |  | Prediction | 15972814
TRPC1 |  | TRPP1 | Inference |  |  |  |  |  | Prediction | 10097141
TRPC1 |  | TRPV4 | Inference |  |  |  |  |  | Prediction | 20705915
TRPC1 |  | TRPV6 | Inference |  |  |  |  |  | Prediction | 22932896
TRPC1 |  | VAMP | Inference |  |  |  |  |  | Prediction | 15121806

(: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top

Validation: In vitro validation
| Assay with recombinant proteins | Reference
--- | --- | ---
TRP channel construct | Interactor construct
TRP channel |  | Interactor | Method | Species | Region | Expression system | Species | Region | Expression system
TRPC1 |  | Calmodulin | Fusion protein-pull down assay | Human | 649-793 | E. coli | Not specified | Full-length | Not specified | 11983166
TRPC1 |  | Calmodulin | Fusion protein-pull down assay | Human | 1-341 | In vitro translation | Not specified | Full-length | E. coli | 12601176
TRPC1 |  | Caspase-4/Caspase-11 | Fusion protein-pull down assay | Not specified | Full-length | In vitro translation | Not specified | p30 domain | E. coli | 24630989
TRPC1 |  | Caveolin-1 | Fusion protein-pull down assay | Human | 1-347 | E. coli | Not specified | Full-length | HSG cell lysates | 12732636
TRPC1 |  | Caveolin-1 | Yeast two-hybrid | Not specified | 317-347 | Yeast | Not specified | Full-length | Yeast | 19897728
TRPC1 |  | D2R | Fusion protein-pull down assay | Human | 638-759 | E. coli | Human | 131-151 | E. coli | 18261457
TRPC1 |  | Enkurin | Fusion protein-pull down assay | Human | Full-length | HEK293 lysates | Mouse | Full-length | HEK293 lysates | 15385169
TRPC1 |  | Enkurin | Yeast two-hybrid | Human | N-terminus | Yeast | Mouse | Full-length | Yeast | 15385169
TRPC1 |  | FKBP52/FKBP4 | Co-immunoprecipitation | Human | Full-length | Sf9 lysates | Human | Full-length | Sf9 lysates | 15199065
TRPC1 |  | FKBP52/FKBP4 | Fusion protein-pull down assay | Human | 1-316 | HEK293 lysates | Human | Full-length | E. coli | 19945390
TRPC1 |  | Homer-3 | Fusion protein-pull down assay | Not used |  | Rat cerebellum lysates | Not specified | Full-length | E. coli | 14505576
TRPC1 |  | I-MFA | Fusion protein-pull down assay | Human | 639-750 | E. coli | Human | Full-length | E. coli | 14530267
TRPC1 |  | NCS-1 | Fusion protein-pull down assay | Human | 639-759 | E. coli | Human | Full-length | E. coli | 18261457
TRPC1 |  | ơ1-syntrophin | Fusion protein-pull down assay | Not used |  | C57BL/10 mouse muscle cell lysates | Mouse | 75-170 | E. coli | 19812031
TRPC1 |  | ơ1-syntrophin | Fusion protein-pull down assay | Not used |  | Mouse myotube lysates | Not specified | 75-170 | E. coli | 17202249
TRPC1 |  | RNF24 | Fusion protein-pull down assay | Not specified | 3-200 | In vitro translation | Human | 98-148 | E. coli | 17850865
TRPC1 |  | SRC | Fusion protein-pull down assay | Mouse | 1-341 | In vitro translation | Chicken | Full-length | E. coli | 16407161
TRPC1 |  | STIM1 | Fusion protein-pull down assay | Not specified | 1-347 | E. coli | Not used |  | HSG cell lysates | 17224452
TRPC1 |  | TRPC3 | Fusion protein-pull down assay | Not specified | 1-347 | E. coli | Not specified | Full-length | HEK293 lysates | 15834157
TRPC1 |  | TRPC3 | Fusion protein-pull down assay | Not used |  | Rabbit fast switch muscle lysates | Human | 38-381 | E. coli | 24613381
TRPC1 |  | TRPC3 | Yeast two-hybrid | Not specified | 1-347 | Yeast | Not specified | 642-842 | Yeast | 15834157
TRPC1 |  | TRPP1 | Fusion protein-pull down assay | Human | 662-750 | E. coli | Human | 680-968 | In vitro translation | 10097141

(: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top

Validation: In vivo validation
| Assay with endogenous proteins | Assay with overexpressed proteins | Reference
--- | --- | --- | ---
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct
TRP channel |  | Interactor | Method | Species | Region | Species | Region
TRPC1 |  | BKca | Co-immunofluorescence staining | Rat aortic vascular smooth muscle cell |  |  |  |  |  | 19168436
TRPC1 |  | BKca | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Human | Full-length | 19168436
TRPC1 |  | BKca | Co-immunoprecipitation | Rat vascular smooth muscle cell |  |  |  |  |  | 19168436
TRPC1 |  | Bkca | Co-immunoprecipitation | Porcine coronary artery |  |  |  |  |  | 25139746
TRPC1 |  | Calcineurin | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 23228564
TRPC1 |  | Caspase-1 | Co-immunoprecipitation |  | HEK293T | Not specified | Full-length | Not specified | Full-length | 24630989
TRPC1 |  | Caspase-4/Caspase-11 | Co-immunoprecipitation |  | HEK293T | Not specified | Full-length | Not specified | Full-length | 24630989
TRPC1 |  | Cav1.2 | Co-immunoprecipitation | Chick embryonic heart lysates |  |  |  |  |  | 21672930
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining |  | HUVEC | Human | Full-length | Mouse | Full-length | 20705915
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining | Rat caudal artery section |  |  |  |  |  | 14551243
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining |  | HSG cell | Not used |  | Not specified | Full-length | 12732636
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining |  | HSG cell | Human | Full-length | Not specified | Full-length | 12732636
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining |  | MDCK | Human | Full-length | Not specified | Full-length | 12732636
TRPC1 |  | Caveolin-1 | Co-immunofluorescence staining | HSG cell |  |  |  |  |  | 19897728
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | C2C12 |  |  |  |  |  | 19351713
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | Rat caudal artery cell |  |  |  |  |  | 14551243
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | HSG cell |  |  |  |  |  | 18430726
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 10766822
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation |  | MDCK | Human | Full-length | Not specified | Full-length | 12732636
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | HSG cell |  |  |  |  |  | 19897728
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 10980191
TRPC1 |  | Caveolin-1 | Fluorescence resonance energy transfer |  | HSG cell | Not specified | Full-length | Not specified | Full-length | 19897728
TRPC1 |  | Caveolin-3 | Co-immunofluorescence staining | Mouse skeletal muscle section |  |  |  |  |  | 18544631
TRPC1 |  | Caveolin-3 | Co-immunoprecipitation | Mouse skeletal muscle cell |  |  |  |  |  | 18544631
TRPC1 |  | Caveolin-3 | Fluorescence resonance energy transfer |  | Mouse skeletal muscle | Human | Full-length | Mouse | Full-length | 18544631
TRPC1 |  | Cortactin | Co-immunoprecipitation | C2C12 |  |  |  |  |  | 19351713
TRPC1 |  | D2R | Co-immunofluorescence staining | Monkey prefrontal cortex |  |  |  |  |  | 18261457
TRPC1 |  | D2R | Co-immunoprecipitation | Rat striatal tissue |  |  |  |  |  | 18261457
TRPC1 |  | D2R | Co-immunoprecipitation | Rat cortex tissue |  |  |  |  |  | 18261457
TRPC1 |  | Dystrophin | Co-immunofluorescence staining | SolC57 |  |  |  |  |  | 17202249
TRPC1 |  | Dystrophin | Co-immunoprecipitation | Mouse hind limb muscle |  |  |  |  |  | 17202249
TRPC1 |  | Dystrophin | Co-immunoprecipitation | SolC57 |  |  |  |  |  | 17202249
TRPC1 |  | FGFR-1 | Co-immunofluorescence staining | Rat neural stem cell |  |  |  |  |  | 15758179
TRPC1 |  | FGFR-1 | Co-immunoprecipitation | Rat telencephalon |  |  |  |  |  | 15758179
TRPC1 |  | FKBP52/FKBP4 | Co-immunoprecipitation | Rat cerebral cortex |  |  |  |  |  | 15199065
TRPC1 |  | FKBP52/FKBP4 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 23228564
TRPC1 |  | FKBP52/FKBP4 | Co-immunoprecipitation | MEG-01 |  |  |  |  |  | 23228564
TRPC1 |  | FKBP52/FKBP4 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 19945390
TRPC1 |  | Gơq/11 | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 10766822
TRPC1 |  | Ƣ-tubulin-5 | Co-immunofluorescence staining |  | ARPE-19 | Human | Full-length | Not used |  | 15935109
TRPC1 |  | Ƣ-tubulin-5 | Co-immunoprecipitation |  | ARPE-19 | Human | Full-length | Not used |  | 15935109
TRPC1 |  | Homer | Co-immunofluorescence staining | Mouse skeletal muscle |  |  |  |  |  | 18268005
TRPC1 |  | Homer | Co-immunoprecipitation | Mouse skeletal muscle |  |  |  |  |  | 18268005
TRPC1 |  | Homer-1 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 14505576
TRPC1 |  | Homer-1 | Co-immunoprecipitation | Rat brain hippocampus |  |  |  |  |  | 14505576
TRPC1 |  | Homer-1 | Co-immunoprecipitation | Rat astrocyte |  |  |  |  |  | 16905188
TRPC1 |  | Homer-1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 22506990
TRPC1 |  | Homer-2 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 14505576
TRPC1 |  | Homer-3 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 14505576
TRPC1 |  | Homer-3 | Co-immunoprecipitation | Rat cerebellum lysates |  |  |  |  |  | 14505576
TRPC1 |  | Homer-3 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 19945390
TRPC1 |  | I-MFA | Co-immunoprecipitation |  | HEK293T | Human | Full-length | Human | Full-length | 14530267
TRPC1 |  | I-MFA | Co-immunoprecipitation | Rat liver tissue |  |  |  |  |  | 14530267
TRPC1 |  | I-MFA | Co-immunoprecipitation | NALM-6 |  |  |  |  |  | 14530267
TRPC1 |  | I-MFA | Co-immunoprecipitation | Rat kidney tissue |  |  |  |  |  | 14530267
TRPC1 |  | I-MFA | Co-immunoprecipitation |  | HEK293T | Mouse | Full-length | Mouse | Full-length | 23770672
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 11336651
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18068335
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 16870612
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18191041
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Rat astrocyte |  |  |  |  |  | 16905188
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18249094
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 15121806
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 12196544
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 23228564
TRPC1 |  | IP3R2 | Co-immunoprecipitation | MEG-01 |  |  |  |  |  | 23228564
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 10970773
TRPC1 |  | IP3R2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 17681754
TRPC1 |  | IP3R3 | Co-immunofluorescence staining | Human keratinocyte |  |  |  |  |  | 15654973
TRPC1 |  | IP3R3 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 14505576
TRPC1 |  | IP3R3 | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 10766822
TRPC1 |  | IP3R3 | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 10980191
TRPC1 |  | IP3R3 | Co-immunoprecipitation | Human keratinocyte |  |  |  |  |  | 15654973
TRPC1 |  | MARCKS | Co-immunoprecipitation | Rabbit portal vein tissue lysates |  |  |  |  |  | 24022404
TRPC1 |  | MGLUR1 | Co-immunoprecipitation |  | CHO | Human | Full-length | Not specified | Not specified | 14614461
TRPC1 |  | MGLUR1 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not specified | Not specified | 14614461
TRPC1 |  | MGLUR1 | Co-immunoprecipitation | Rat cerebellum lysates |  |  |  |  |  | 14614461
TRPC1 |  | MxA | Co-immunoprecipitation |  | HEK293T | Human | Full-length | Human | Full-length | 15757897
TRPC1 |  | ơ-actinin | Co-immunofluorescence staining | Rat ventricular myocytes |  |  |  |  |  | 24146259
TRPC1 |  | ơ-actinin-1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 17892531
TRPC1 |  | ơ1-syntrophin | Co-immunoprecipitation | SolD6 |  |  |  |  |  | 19812031
TRPC1 |  | ơ1-syntrophin | Co-immunoprecipitation | C57BL/10 mouse muscle cell |  |  |  |  |  | 19812031
TRPC1 |  | ơ1-syntrophin | Co-immunoprecipitation | Mouse muscle lysates |  |  |  |  |  | 17202249
TRPC1 |  | ơ1-syntrophin | Co-immunoprecipitation |  | SolC1 | Not used |  | Mouse | Full-length | 17202249
TRPC1 |  | ơ1-syntrophin | Co-immunoprecipitation |  | SolD6 | Not used |  | Mouse | Full-length | 17202249
TRPC1 |  | Orai1 | Co-immunoprecipitation |  | HEK293T | Mouse | Full-length | Human | Full-length | 23770672
TRPC1 |  | Orai1 | Co-immunoprecipitation | HEK293 |  |  |  |  |  | 18326500
TRPC1 |  | Orai1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18644792
TRPC1 |  | Orai1 | Co-immunoprecipitation | Human atrial myocyte |  |  |  |  |  | 23686296
TRPC1 |  | Orai1 | Co-immunoprecipitation | Human parathyroid tissue |  |  |  |  |  | 20194530
TRPC1 |  | Orai2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 22640869
TRPC1 |  | Orai3 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 22640869
TRPC1 |  | PLCƣ1 | Co-immunofluorescence staining | Human keratinocyte |  |  |  |  |  | 15654973
TRPC1 |  | PLCƣ1 | Co-immunoprecipitation | Human keratinocyte |  |  |  |  |  | 15654973
TRPC1 |  | PMCA | Co-immunoprecipitation |  | HSG cell | Human | Full-length | Not used |  | 11983166
TRPC1 |  | Protein 4.1 | Co-immunoprecipitation | Rat pumonary aortic endothelial cell |  |  |  |  |  | 22534489
TRPC1 |  | RhoA | Co-immunofluorescence staining |  | Human pulmonary arterial endothelial cell | Not used |  | Not specified | Full-length | 12766172
TRPC1 |  | RhoA | Co-immunoprecipitation | Human pulmonary arterial endothelial cell |  |  |  |  |  | 12766172
TRPC1 |  | RyR1 | Co-immunoprecipitation | Mouse skeletal myotube lysates |  |  |  |  |  | 18215135
TRPC1 |  | SERCA2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18068335
TRPC1 |  | SERCA2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18191041
TRPC1 |  | SERCA3 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18068335
TRPC1 |  | SERCA3 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18191041
TRPC1 |  | SNAP25 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 15121806
TRPC1 |  | STIM1 | Co-immunofluorescence staining |  | HEK293 | Human | Full-length | Human | Full-length | 16906149
TRPC1 |  | STIM1 | Co-immunofluorescence staining | Mouse pulmonary arterial smooth muscle cell |  |  |  |  |  | 23034388
TRPC1 |  | STIM1 | Co-immunofluorescence staining |  | HSG cell | Human | Full-length | Not specified | Full-length | 17224452
TRPC1 |  | STIM1 | Co-immunofluorescence staining | HSG cell |  |  |  |  |  | 19897728
TRPC1 |  | STIM1 | Co-immunofluorescence staining | Human saphenous vein vascular smooth muscle cell |  |  |  |  |  | 18802022
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Not used |  | 19228695
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 16870612
TRPC1 |  | STIM1 | Co-immunoprecipitation | Mouse pulmonary arterial smooth muscle cell |  |  |  |  |  | 19332490
TRPC1 |  | STIM1 | Co-immunoprecipitation | Rat brain tissue |  |  |  |  |  | 16906149
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Human | Full-length | 16906149
TRPC1 |  | STIM1 | Co-immunoprecipitation | Mouse pulmonary arterial smooth muscle cell |  |  |  |  |  | 23034388
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18249094
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | HEK293 | Not specified | Full-length | Human | Full-length | 24464579
TRPC1 |  | STIM1 | Co-immunoprecipitation | Mouse bone marrow derived macrophages |  |  |  |  |  | 25013939
TRPC1 |  | STIM1 | Co-immunoprecipitation | HEK293 |  |  |  |  |  | 18326500
TRPC1 |  | STIM1 | Co-immunoprecipitation | HSG cell |  |  |  |  |  | 18430726
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | HEK293 | Not used |  | Not specified | Full-length | 17224452
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | A7r5 | Not used |  | Not specified | Full-length | 17224452
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18644792
TRPC1 |  | STIM1 | Co-immunoprecipitation | HEK293 |  |  |  |  |  | 23395841
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human atrial myocyte |  |  |  |  |  | 23686296
TRPC1 |  | STIM1 | Co-immunoprecipitation | HSG cell |  |  |  |  |  | 19897728
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | HEK293T | Rat | Full-length | Rat | Full-length | 22201561
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human saphenous vein vascular smooth muscle cell |  |  |  |  |  | 18802022
TRPC1 |  | STIM1 | Co-immunoprecipitation |  | Human saphenous vein vascular smooth muscle cell | Human | Full-length | Not specified | Full-length | 18802022
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 17892531
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human parathyroid tissue |  |  |  |  |  | 20194530
TRPC1 |  | STIM1 | Co-immunoprecipitation | SH-SY5Y |  |  |  |  |  | 22446186
TRPC1 |  | STIM1 | Co-immunoprecipitation | HSG cell |  |  |  |  |  | 20488539
TRPC1 |  | STIM1 | Co-immunoprecipitation | Rat normal small intestine cell line IEC-6 |  |  |  |  |  | 22592407
TRPC1 |  | STIM1 | Co-immunoprecipitation | Rat normal small intestine cell line IEC-6 (IEC-Cdx2L1 stable cell) |  |  |  |  |  | 22592407
TRPC1 |  | STIM1 | Co-immunoprecipitation | Caco-2 cell |  |  |  |  |  | 22592407
TRPC1 |  | STIM2 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 22640869
TRPC1 |  | TRPA1 | Co-immunoprecipitation | MEG-01 |  |  |  |  |  | 23994313
TRPC1 |  | TRPC3 | Co-immunoprecipitation | HSY cell |  |  |  |  |  | 15834157
TRPC1 |  | TRPC3 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 19260825
TRPC1 |  | TRPC3 | Co-immunoprecipitation | HEK293 |  |  |  |  |  | 15972814
TRPC1 |  | TRPC3 | Co-immunoprecipitation | Rat carotid artery smooth muscle cell |  |  |  |  |  | 19502552
TRPC1 |  | TRPC3 | Co-immunoprecipitation | Mouse skeletal myotube lysates |  |  |  |  |  | 18215135
TRPC1 |  | TRPC3 | Co-immunoprecipitation | Mouse primary skeletal myotubes |  |  |  |  |  | 24613381
TRPC1 |  | TRPC3 | Co-immunoprecipitation |  | HEK293T | Human | Full-length | Human | Full-length | 9215637
TRPC1 |  | TRPC3 | Co-immunoprecipitation | C2C12 |  |  |  |  |  | 21996795
TRPC1 |  | TRPC3 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Human | Full-length | 17486119
TRPC1 |  | TRPC3 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 12857742
TRPC1 |  | TRPC4 | Co-immunofluorescence staining | BAE-1 |  |  |  |  |  | 16818374
TRPC1 |  | TRPC4 | Co-immunofluorescence staining | Human glomerular mesangial cell |  |  |  |  |  | 16418302
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 11301024
TRPC1 |  | TRPC4 | Co-immunoprecipitation | BAE-1 |  |  |  |  |  | 16818374
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Human glomerular mesangial cell |  |  |  |  |  | 19307462
TRPC1 |  | TRPC4 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Mouse | Full-length | 12032305
TRPC1 |  | TRPC4 | Co-immunoprecipitation | C57BL/10 mouse muscle cell |  |  |  |  |  | 19812031
TRPC1 |  | TRPC4 | Co-immunoprecipitation |  | Sf9 | Human | Full-length | Bovine | Full-length | 12377790
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Rat brain synaptome |  |  |  |  |  | 12377790
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 16270640
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Mouse lung endothelium cell |  |  |  |  |  | 17416589
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Human glomerular mesangial cell |  |  |  |  |  | 16418302
TRPC1 |  | TRPC4 | Co-immunoprecipitation |  | Mouse lung endothelial cell | Mouse | Full-length | Mouse | Full-length | 22210847
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 12857742
TRPC1 |  | TRPC4 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 17892531
TRPC1 |  | TRPC4 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 12032305
TRPC1 |  | TRPC4 | Fluorescence resonance energy transfer | Rat pumonary aortic endothelial cell |  |  |  |  |  | 22534489
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 11301024
TRPC1 |  | TRPC5 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Mouse | Full-length | 11301024
TRPC1 |  | TRPC5 | Co-immunoprecipitation |  | Sf9 | Human | Full-length | Mouse | Full-length | 12377790
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rat brain synaptome |  |  |  |  |  | 12377790
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rabbit coronary artery |  |  |  |  |  | 18356201
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rabbit mesenteric artery |  |  |  |  |  | 18356201
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rabbit portal vein |  |  |  |  |  | 18356201
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 16270640
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Mouse vascular smooth muscle cell |  |  |  |  |  | 21968068
TRPC1 |  | TRPC5 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 12857742
TRPC1 |  | TRPC5 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 12032305
TRPC1 |  | TRPC6 | Co-immunofluorescence staining | Human glomerular mesangial cell |  |  |  |  |  | 16418302
TRPC1 |  | TRPC6 | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 18191041
TRPC1 |  | TRPC6 | Co-immunoprecipitation | Human glomerular mesangial cell |  |  |  |  |  | 16418302
TRPC1 |  | TRPC6 | Co-immunoprecipitation | Rat brain microsome |  |  |  |  |  | 12857742
TRPC1 |  | TRPC7 | Co-immunoprecipitation | HEK293 |  |  |  |  |  | 15972814
TRPC1 |  | TRPP1 | Co-immunofluorescence staining |  | HEK293 tsA 201 | Human | Full-length | Human | Full-length | 19850920
TRPC1 |  | TRPP1 | Co-immunofluorescence staining | mIMCD-3 |  |  |  |  |  | 18323855
TRPC1 |  | TRPP1 | Co-immunofluorescence staining |  | HEK293T | Human | Full-length | Human | Full-length | 10097141
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293T | Human | Full-length | Not specified | Not specified | 14530267
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | Human glomerular mesangial cell | Human | Full-length | Not used |  | 18256307
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293 | Mouse | Full-length | Human | Full-length | 19812035
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293 tsA 201 | Human | Full-length | Human | Full-length | 19850920
TRPC1 |  | TRPP1 | Co-immunoprecipitation | Rat kidney tissue |  |  |  |  |  | 18323855
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293 tsA 201 | Human | Full-length | Human | Full-length | 20682256
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | Rat mesenteric artery endothelial cell | Human | Full-length | Human | Full-length | 25114176
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Human | Full-length | 25114176
TRPC1 |  | TRPP1 | Co-immunoprecipitation |  | HEK293T | Human | Full-length | Human | Full-length | 10097141
TRPC1 |  | TRPP1 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Human | Full-length | 25114176
TRPC1 |  | TRPV4 | Co-immunofluorescence staining |  | HEK293 | Human | Full-length | Mouse | Full-length | 20093626
TRPC1 |  | TRPV4 | Co-immunofluorescence staining | Rat mesenteric artery endothelial cell lysates |  |  |  |  |  | 20093626
TRPC1 |  | TRPV4 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Mouse | Full-length | 20093626
TRPC1 |  | TRPV4 | Co-immunoprecipitation | Rat mesenteric artery endothelial cell lysates |  |  |  |  |  | 20093626
TRPC1 |  | TRPV4 | Co-immunoprecipitation |  | Rat mesenteric artery endothelial cell | Human | Full-length | Mouse | Full-length | 25114176
TRPC1 |  | TRPV4 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Mouse | Full-length | 25114176
TRPC1 |  | TRPV4 | Co-immunoprecipitation | Porcine coronary artery |  |  |  |  |  | 25139746
TRPC1 |  | TRPV4 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 20093626
TRPC1 |  | TRPV4 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 20705915
TRPC1 |  | TRPV4 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 21871867
TRPC1 |  | TRPV4 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Mouse | Full-length | 25114176
TRPC1 |  | TRPV6 | Co-immunoprecipitation |  | HEK293 | Human | Full-length | Rat | Full-length | 22932896
TRPC1 |  | TRPV6 | Co-immunoprecipitation | LNCaP |  |  |  |  |  | 25172921
TRPC1 |  | TRPV6 | Fluorescence resonance energy transfer |  | HEK293 | Human | Full-length | Rat | Full-length | 22932896
TRPC1 |  | VAMP | Co-immunoprecipitation | Human platelets |  |  |  |  |  | 15121806

(: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top

Characterization
| Binding region mapping | Stoichiometry | Affinity (Kd) | Reference
--- | --- | --- | --- | ---
TRP channel | Interactor
TRP channel |  | Interactor | Method | Species | Region | Species | Region
TRPC1 |  | Calmodulin | Fluorescence probe labeling | Human | 720-749 | Not specified | Not determined |  | 30 nM | 11290752
TRPC1 |  | Calmodulin | Fusion protein-pull down assay | Human | 719-751 | Not specified | Not determined |  |  | 11290752
TRPC1 |  | Calmodulin | Fusion protein-pull down assay | Human | 719-751 | Not specified | Not determined |  |  | 11983166
TRPC1 |  | Calmodulin | Fusion protein-pull down assay | Human | 758-793 | Not specified | Not determined |  |  | 11983166
TRPC1 |  | Caspase-4/Caspase-11 | Co-immunoprecipitation | Not specified | 1-318 | Not specified | p30 domain |  |  | 24630989
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | Human | 781-789 | Human | Not determined |  |  | 16822931
TRPC1 |  | Caveolin-1 | Co-immunoprecipitation | Human | 781-789 | Human | 82-101 |  |  | 19052258
TRPC1 |  | Caveolin-1 | Fusion protein-pull down assay | Human | Not determined | Human | 82-101 |  |  | 16822931
TRPC1 |  | Caveolin-1 | Yeast two-hybrid | Human | 271-349 | Not specified | Not determined |  |  | 12732636
TRPC1 |  | D2R | Yeast two-hybrid | Human | 726-745 | Human | 131-151 |  |  | 18261457
TRPC1 |  | Homer-3 | Co-immunoprecipitation | Human | 645-648 | Human | EVH1 domain |  |  | 14505576
TRPC1 |  | Homer-3 | Fusion protein-pull down assay | Human | 20-23 | Not specified | EVH1 domain |  |  | 14505576
TRPC1 |  | IP3R3 | Co-immunoprecipitation | Human | 781-789 | Human | Not determined |  |  | 19052258
TRPC1 |  | IP3R3 | Co-immunoprecipitation | Human | 645-648 | Human | Not determined |  |  | 14505576
TRPC1 |  | IP3R3 | Fusion protein-pull down assay | Human | 719-751 | Human | 669-698 |  |  | 11290752
TRPC1 |  | ơ1-syntrophin | Fusion protein-pull down assay | Mouse | Not determined | Not specified | 75-170 |  |  | 17202249
TRPC1 |  | ơ1-syntrophin | Fusion protein-pull down assay | Mouse | Not determined | Mouse | 75-170 |  |  | 19812031
TRPC1 |  | STIM1 | Co-immunoprecipitation | Rat | Not determined | Rat | 1798-1887 |  |  | 22201561
TRPC1 |  | STIM1 | Co-immunoprecipitation | Human | Not determined | Human | 251-535 |  |  | 16906149
TRPC1 |  | STIM1 | Fusion protein-pull down assay | Human | 1-347 | Human | Not determined |  |  | 17224452
TRPC1 |  | STIM1 | Fusion protein-pull down assay | Human | Not determined | Human | 251-535 |  |  | 16906149
TRPC1 |  | TRPC3 | Yeast two-hybrid | Not specified | 1-73 | Not specified | 1-341 |  |  | 15834157
TRPC1 |  | TRPP1 | Atomic force microscopy(AFM) analysis |  |  |  |  | 2:2 |  | 19850920
TRPC1 |  | TRPP1 | Atomic force microscopy(AFM) analysis |  |  |  |  | 2:2 |  | 19193631
TRPC1 |  | TRPP1 | Co-immunoprecipitation | Human | Not determined | Human | 1-643 |  |  | 10097141
TRPC1 |  | TRPP1 | Co-immunoprecipitation | Human | Not determined | Human | 679-968 |  |  | 10097141
TRPC1 |  | TRPP1 | Yeast two-hybrid | Human | 639-750 | Human | 822-895 |  |  | 10097141
TRPC1 |  | TRPV4 | Fluorescence resonance energy transfer |  |  |  |  | 2:2 |  | 21871867
TRPC1 |  | TRPV6 | Fluorescence resonance energy transfer | Human | 1-193 | Rat | 1-198 |  |  | 22932896

(: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top

Functional consequence
TRP channel |  | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference
--- | --- | --- | --- | --- | --- | --- | ---
TRPC1 |  | Calmodulin | Calcium measurement |  |  | Inhibition | 11983166
TRPC1 |  | Calmodulin | Patch clamp |  |  | Inhibition | 11983166
TRPC1 |  | Caveolin-1 | Cell surface biotinylation |  | Increase in plasma membrane level |  | 19897728
TRPC1 |  | D2R | Cell surface biotinylation |  | Increase in plasma membrane level |  | 18261457
TRPC1 |  | FKBP52/FKBP4 | Patch clamp |  |  | Inhibition | 19945390
TRPC1 |  | Ƣ-tubulin-5 | Calcium measurement |  |  | Inhibition | 15935109
TRPC1 |  | Ƣ-tubulin-5 | Co-immunofluorescence staining |  | Increase in plasma membrane level |  | 15935109
TRPC1 |  | I-MFA | Patch clamp |  |  | Inhibition | 14530267
TRPC1 |  | I-MFA | Patch clamp |  |  | Desensitization | 23770672
TRPC1 |  | IP3R2 | Calcium measurement |  |  | Activation | 12196544
TRPC1 |  | IP3R2 | Patch clamp |  |  | Activation | 12196544
TRPC1 |  | MARCKS | Patch clamp |  |  | Inhibition | 24022404
TRPC1 |  | MGLUR1 | Patch clamp |  |  | Activation | 14614461
TRPC1 |  | PLCƣ1 | Calcium measurement |  |  | Activation | 15654973
TRPC1 |  | STIM1 | Patch clamp |  |  | Activation | 16906149
TRPC1 |  | TRPC3 | Patch clamp |  |  | New channel creation | 10882720
TRPC1 |  | TRPC4 | Patch clamp |  |  | New channel creation | 11301024
TRPC1 |  | TRPC4 | Patch clamp |  |  | New channel creation | 22144671
TRPC1 |  | TRPC5 | Patch clamp |  |  | New channel creation | 11301024
TRPC1 |  | TRPC5 | Patch clamp |  |  | New channel creation | 12857742
TRPC1 |  | TRPP1 | Patch clamp |  |  | New channel creation | 18323855
TRPC1 |  | TRPP1 | Patch clamp |  |  | New channel creation | 25114176
TRPC1 |  | TRPV4 | Cell surface biotinylation |  | Increase in plasma membrane level |  | 20705915
TRPC1 |  | TRPV4 | Co-immunofluorescence staining |  | Increase in plasma membrane level |  | 20705915
TRPC1 |  | TRPV4 | Patch clamp |  |  | New channel creation | 25114176

(: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Name Email Title* Comment* TRP
/ Interactor
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