Methsuximide for intractable childhood seizures.
 Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy.
 In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency.
 No serious or irreversible adverse effects were seen.
 Methsuximide is frequently overlooked and may be an effective adjunctive antiepileptic for children with intractable seizures.
